報告題目：Each fungus has its own repertoire of secondary metabolites:

What are their role in the lifestyle of the grey mould fungus Botrytis cinerea ?（真菌次生代謝產物對其生活方式的影響）

報告人：Dr Muriel Viaud

報告時間：2018年9月13日（周四）上午10:30-11:30

報告地點：學15-612

報告人簡介：

一、教育及工作經歷

1992 Master in Genetics and Molecular Biology, Université Paris-Sud, France.

1997 PhD in Microbial Ecology, University of Lyon I, France.

2016 Habilitation thesis, University Paris-Saclay, France.

二、主要研究方向：

(1) Secondary metabolites acting as virulence factors.

(2) Regulation of secondary metabolism and necrotrophic development through transcription factors and modifications of the chromatin structure.

(3) Genomic bases of partial host specialization in a polyphagous fungus.

三、代表性論文：

Izquierdo-Bueno I, Gonza?lez-Rodri?guez VE, Simon A, Dalmais B, Pradier JM, Le Pe?cheur P, Mercier A, Walker AS, Garrido C, Collado IG,Viaud M.(2018). Biosynthesis of abscisic acid in fungi: identification of a sesquiterpene cyclase as the key enzyme inBotrytis cinerea. Environ Microbiol. 20(7):2469-2482.

Porquier A, Morgant G, Moraga J, Dalmais B, Luyten I, Simon A, Pradier JM, Amselem J, Collado IG,Viaud M(2016). The botrydial biosynthetic gene cluster ofBotrytis cinereadisplays a bipartite genomic structure and is controlled by the BcBot6 Zn(II)2Cys6 protein. Fung Genet Biol 96 : 33-46.

Viaud M, Schumacher J, Porquier A, Simon, A (2016). Regulation of secondary metabolism in the grey mould fungusBotrytis cinerea. In: “Host - Pathogen Interaction: Microbial Metabolism, Pathogenicity and Antiinfectives, Part B: Adaptation of microbial metabolism in host/fungus-interactions”. G Unden, E Thines & A Schu?ffler eds. Wiley-Blackwell.

Kelloniemi J, Trouvelot S, He?loir MC, Simon A, Dalmais B, Frettinger P, Cimerman A, Fermaud M, Roudet J, Baulande S, Bruel C, Choquer M, Couvelard L, Duthieuw M, Ferrarini A, Flors V, Le Pe?cheur P, Loisel E, Morgant G, Poussereau N, Pradier JM, Rascle C, Trda? L, Poinssot B,Viaud M(2015). Analysis of the molecular dialogue between gray mold (Botrytis cinerea) and grapevine (Vitis vinifera) reveals a clear shift in defense mechanisms during berry ripening. Mol Plant Microb Interact. 28(11):1167-80.

Simon A, Dalmais B, Morgant G,Viaud M(2013) Screening of aBotrytis cinereaone-hybrid library reveals a Cys2His2 transcription factor involved in the regulation of secondary metabolism gene clusters. Fung Genet Biol 52:9-19.

Viaud M, Adam Blondon AF, Amselem J, Bally P, Cimerman A, Dalmais B, Lapalu N, Lebrun MH, Poinssot B,Pradier JM, Simon A. 2012. Le ge?nome deBotrytis de?crypte?. Revue des ?nologues 142:9-11.

Pinedo C, Wang CM, Pradier JM, Dalmais B, Choquer M, Le Pe?cheur P, Morgant G, Collado IG, Cane DE,Viaud M(2008). Sesquiterpene synthase from the botrydial biosynthetic gene cluster of the phytopathogenBotrytis cinerea. ACS Chem Biol 3:791-801.

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農業與食品科學學院

2018年9月11日